Janet Douglas Countess Bothwell was born to James Douglas 1st Earl Morton -1493 and Joan Stewart Countess Morton 1428-1486. She a great x 3 granddaughter of King Edward III of England. Coefficient of inbreeding 3.14%. 
In 1479 Adam Hepburn 1st Lord Hailes (age 46) died in Bothwell. His son [her future husband] Patrick Hepburn 1st Earl Bothwell (age 27) succeeded 2nd Lord Hailes. Janet Douglas Countess Bothwell by marriage Lord Hailes.
Before Feb 1481 Patrick Hepburn 1st Earl Bothwell (age 29) and Janet Douglas Countess Bothwell were married. She the daughter of James Douglas 1st Earl Morton -1493 and Joan Stewart Countess Morton 1428-1486 (age 53). She a great x 3 granddaughter of King Edward III of England.
On 17 Oct 1488 [her husband] Patrick Hepburn 1st Earl Bothwell (age 36) was created 1st Earl Bothwell. Janet Douglas Countess Bothwell by marriage Countess Bothwell.
On 21 Feb 1491 [her husband] Patrick Hepburn 1st Earl Bothwell (age 39) and Margaret Gordon Countess Bothwell were married. She by marriage Countess Bothwell. She the daughter of George Gordon 2nd Earl Huntley (age 35).
On 18 Oct 1508 [her husband] Patrick Hepburn 1st Earl Bothwell (age 56) died. His son Adam Hepburn 2nd Earl Bothwell -1513 succeeded 2nd Earl Bothwell.
[her daughter] Joanna Hepburn Lady Seton was born to Patrick Hepburn 1st Earl Bothwell and Janet Douglas Countess Bothwell.
Paternal Family Tree: Douglas
Maternal Family Tree: Aoife NI Diarmait Macmurrough Countess Pembroke and Buckingham 1145-1188
Descendants Family Trees:
King Edward III of England 1312-1377
John of Gaunt 1st Duke Lancaster 1340-1399
Eleanor Plantagenet Countess Arundel and Surrey 1318-1372
Richard Fitzalan 10th Earl Arundel 8th Earl Surrey 1306-1376
Thomas Holland 2nd Earl Kent 1350-1397
Katherine Roet Duchess Lancaster 1350-1403
Kings Wessex: Great x 12 Grand Daughter of King Edmund "Ironside" I of England
Kings Gwynedd: Great x 8 Grand Daughter of Owain "Great" King Gwynedd 1100-1170
Kings Seisyllwg: Great x 14 Grand Daughter of Hywel "Dda aka Good" King Seisyllwg King Deheubarth
Kings Powys: Great x 9 Grand Daughter of Maredudd ap Bleddyn King Powys 1047-1132
Kings England: Great x 3 Grand Daughter of King Edward III of England
Kings Scotland: Great x 4 Grand Daughter of Robert "The Bruce" I King Scotland
Kings Franks: Great x 9 Grand Daughter of Louis VII King Franks
Kings France: Great x 5 Grand Daughter of Philip "The Fair" IV King France
Great x 4 Grandfather: James Douglas of Hermiston and Lothian
Great x 3 Grandfather: John Douglas of Lothian
Great x 4 Grandmother: Joan
Great x 2 Grandfather: James Douglas of Dalkeith
Great x 4 Grandfather: John Graham
Great x 3 Grandmother: Agnes Graham
Great x 1 Grandfather: James Douglas 1st Lord Dalkeith
Great x 3 Grandfather: Patrick Dunbar 9th Earl March 1285-1369
Great x 2 Grandmother: Agnes Dunbar
Great x 4 Grandmother: Isabella Stewart Countess Moray
GrandFather: James Douglas 6 x Great Grand Son of King John "Lackland" of England
Great x 4 Grandfather: Walter Stewart 6th High Steward
Great x 3 Grandfather: King Robert II of Scotland 3 x Great Grand Son of King John "Lackland" of England
Great x 4 Grandmother: Marjory Bruce 2 x Great Grand Daughter of King John "Lackland" of England
Great x 2 Grandfather: King Robert III of Scotland 1337-1406 4 x Great Grand Son of King John "Lackland" of England
Great x 1 Grandmother: Elizabeth Stewart Lady Dalkeith 5 x Great Grand Daughter of King John "Lackland" of England
Father: James Douglas 1st Earl Morton -1493 7 x Great Grand Son of King John "Lackland" of England
Great x 1 Grandfather: James Gifford
GrandMother: Elizabeth Gifford
Janet Douglas Countess Bothwell 3 x Great Grand Daughter of King Edward III of England
Great x 4 Grandfather: James Stewart 5th High Steward
Great x 3 Grandfather: Walter Stewart 6th High Steward
Great x 2 Grandfather: King Robert II of Scotland 3 x Great Grand Son of King John "Lackland" of England
Great x 4 Grandfather: Robert "The Bruce" I King Scotland 5 x Great Grand Son of King Henry I "Beauclerc" England
Great x 3 Grandmother: Marjory Bruce 2 x Great Grand Daughter of King John "Lackland" of England
Great x 4 Grandmother: Isabella Mar Great Grand Daughter of King John "Lackland" of England
Great x 1 Grandfather: King Robert III of Scotland 1337-1406 4 x Great Grand Son of King John "Lackland" of England
GrandFather: King James I of Scotland 5 x Great Grand Son of King John "Lackland" of England
Mother: Joan Stewart Countess Morton 1428-1486 2 x Great Grand Daughter of King Edward III of England
Great x 4 Grandfather: King Edward II of England
Son of King Edward "Longshanks" I of England
Great x 3 Grandfather: King Edward III of England Son of King Edward II of England
Great x 4 Grandmother: Isabella of France Queen Consort England
4 x Great Grand Daughter of King Henry "Curtmantle" II of England
Great x 2 Grandfather: John of Gaunt 1st Duke Lancaster Son of King Edward III of England
Great x 4 Grandfather: William Hainault I Count Hainault III Count Avesnes III Count Holland II Count Zeeland 6 x Great Grand Son of King William "Conqueror" I of England
Great x 3 Grandmother: Philippa of Hainault Queen Consort England 5 x Great Grand Daughter of King Henry "Curtmantle" II of England
Great x 4 Grandmother: Joan Valois Countess Zeeland Holland Avesnes and Hainault 4 x Great Grand Daughter of King Henry "Curtmantle" II of England
Great x 1 Grandfather: John Beaufort 1st Marquess Somerset and Dorset 
Grand Son of King Edward III of England
Great x 3 Grandfather: Giles "Payne" Roet
Great x 2 Grandmother: Katherine Roet Duchess Lancaster
GrandMother: Joan Beaufort Queen Consort Scotland Great Grand Daughter of King Edward III of England
Great x 4 Grandfather: Robert Holland 1st Baron Holand
Great x 3 Grandfather: Thomas Holland 1st Earl Kent 4 x Great Grand Son of King Henry "Curtmantle" II of England
Great x 4 Grandmother: Maud Zouche Baroness Holand
3 x Great Grand Daughter of King Henry "Curtmantle" II of England
Great x 2 Grandfather: Thomas Holland 2nd Earl Kent Great Grand Son of King Edward "Longshanks" I of England
Great x 4 Grandfather: Edmund of Woodstock 1st Earl Kent Son of King Edward "Longshanks" I of England
Great x 3 Grandmother: Joan "Fair Maid of Kent" Princess Wales Grand Daughter of King Edward "Longshanks" I of England
Great x 4 Grandmother: Margaret Wake Countess Kent
3 x Great Grand Daughter of King John "Lackland" of England
Great x 1 Grandmother: Margaret Holland Duchess Clarence 2 x Great Grand Daughter of King Edward "Longshanks" I of England
Great x 4 Grandfather: Edmund Fitzalan 9th Earl Arundel
4 x Great Grand Son of King John "Lackland" of England
Great x 3 Grandfather: Richard Fitzalan 10th Earl Arundel 8th Earl Surrey 5 x Great Grand Son of King John "Lackland" of England
Great x 4 Grandmother: Alice Warenne Countess Arundel
Great x 2 Grandmother: Alice Fitzalan Countess Kent 1350-1416 2 x Great Grand Daughter of King Henry III of England
Great x 4 Grandfather: Henry Plantagenet 3rd Earl of Leicester 3rd Earl Lancaster Grand Son of King Henry III of England
Great x 3 Grandmother: Eleanor Plantagenet Countess Arundel and Surrey
Great Grand Daughter of King Henry III of England
Great x 4 Grandmother: Maud Chaworth