On 09 Aug 1744 James Brydges 1st Duke Chandos (age 71) died at Cannons House Little Stanmore. He was buried at Chandos Mausoleum Church of St Lawrence Whitchurch Lane Little Stanmore. His son Henry Brydges 2nd Duke Chandos (age 36) succeeded 2nd Duke Chandos, 2nd Marquess Carnarvon, 2nd Earl Carnarvon, 2nd Viscount Wilton, 10th Baron Chandos of Sudeley, 5th Baronet Brydges of Wilton in Herefordshire.

On 28 Nov 1771 Henry Brydges 2nd Duke Chandos (age 63) died. His son James Brydges 3rd Duke Chandos (age 39) succeeded 3rd Duke Chandos, 3rd Marquess Carnarvon, 3rd Earl Carnarvon, 3rd Viscount Wilton, 11th Baron Chandos of Sudeley, 6th Baronet Brydges of Wilton in Herefordshire.

On 29 Sep 1789 James Brydges 3rd Duke Chandos (age 57) died without male issue. Duke Chandos, Marquess Carnarvon, Earl Carnarvon, Viscount Wilton, Baron Chandos of Sudeley and Baronet Brydges of Wilton in Herefordshire extinct. His wife Anne Eliza Gamon Duchess Chandos (age 52) had pulled away a chair, whether inadvertently or deliberately is unknown, he was about to sit in causing him injuries from which he ultimately died. She was, thereafter, declared a lunatic and confined to their London home, 2 Queen Anne Street aka Chandos House Marylebone.